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Resveratrol

Resveratrol 

Resveratrol

Product name:Resveratrol

Source:giant knotweed

CAS no:501-36-0

Molecular Formula:C14H12O3

Test Methold: HPLC

 

 About resveratrol

Resveratrol is a polyphenol compounds, mainly derived from grape (red wine), giant knotweed, peanut, mulberry and other plants.Resveratrol is a kind of biological strong natural polyphenols, also known as the three phenol stilbene, is cancer chemoprevention agents, is also to reduce platelet aggregation, the prevention and treatment of atherosclerosis, disease of heart head blood-vessel chemoprophylaxis agent.The United States department of agriculture research results show that the peanut and ren also contains a considerable amount of resveratrol in red.

 

Resveratrol Function:

1. Have antiarrhythmic action and to relieve asthma.

2. Lower blood pressure and relax vascular smooth. 

3. The function of drying dampness and kill worms.

4.Expel cold and the wind,to warm the kidney and strengthen the yin.

5.Antifugal and antivirotic. 

 

 
Resveratrol Application:

1. Applied in food field, often used as additives, with distinct fragrance smell, it can promote digestion and increase appetite;

2. Applied in daily necessities field, aslo added into a large amount of oral cleaning products, such as dentifrices, mouthwash and tooth powder;

3. Applied in pharmaceutical field, because of the function of inhibition and paralysis to sensory nerve endings, it can be used as counter irritant.

 

For more product information pls kindly contact sales09@staherb.cn

 

 

Product Analysis

 

 

Items

Standards

Results

Physical Analysis

   

Description

White Fine Powder Complies

Assay

Trihydroxystilbene 98% 98.12%

Mesh Size

100 % pass 80 mesh Complies

Ash

≤ 5.0% 2.85%
Loss on Drying ≤ 5.0% 2.85%
Chemical Analysis    
Heavy Metal ≤ 10.0 mg/kg Complies
Pb ≤ 2.0 mg/kg Complies
As ≤ 1.0 mg/kg Complies
Hg ≤ 0.1 mg/kg Complies
Microbiological Analysis    
Residue of Pesticide Negative Negative
Total Plate Count ≤ 1000cfu/g Complies
Yeast&Mold ≤ 100cfu/g Complies
E.coil Negative Negative
Salmonella Negative Negative
 
  1. References:
  2. 1.Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5: 493–506
  3. 2.Bemis DL, Katz AE, Buttyan R (2006) Clinical trials of natural products as chemopreventive agents for prostate cancer. Expert Opin Investig Drugs 15: 1191–200
  4. 3.Aggarwal BB, Bhardwaj A, Aggarwal RS et al. (2004) Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res 24: 2783–2840
  5. 4.Joe AK, Liu H, Suzui M et al. (2002) Resveratrol induces growth inhibition, S phase arrest, apoptosis and changes biomarker expression in several human cancer cell lines. Clin Cancer Res 8: 893–903
  6. 5.Soleas GJ, Grass L, Josephy PD et al. (2006) A comparison of the anticarcinogenic properties of four red wine polyphenols. Clin Biochem 39: 492–497
  7. 6.Providencia R (2006) Cardiovascular protection from alcoholic drinks: scientific basis of the French Paradox. Rev Port Cardiol 25: 1043–1058
  8. 7.Ovesna Z, Kozics K, Bader Y et al. (2006) Antioxidant activity of resveratrol, piceatannol and 3,3’,4,4’,5,5’-hexahydroxy-trans-stilbene in three leukemia cell lines. Oncol Rep 16: 617–624
  9. 8.Athar M, Back JH, Tang X et al. (2007) Resveratrol: A review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol (in press)
  10. 9.Ovesna Z, Horvathova-Kozics K (2005) Structure-activity relationship of trans-resveratrol and its analogues. Neoplasma 52: 450–455
  11. 10.Pezutto JM (2004) Resveratrol: a whiff that induces a biologically specific tsunami. Cancer Biol Ther 3: 889–890
  12. 11.Aziz MH, Nihal M, Fu VX et al. (2006) Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3’-kinase/Akt pathway and Bcl-family proteins. Mol Cancer Ther 5: 1335–1341
  13. 12.Liao Z, Mason KA, Milas L (2007) Cyclo-oxygenase-2 and its inhibition in cancer: is there a role? Drugs 67: 821–845
  14. 13.Horvath Z, Murias M, Saiko P et al. (2006) Cytotoxic and biochemical effects of 3,3’,4,4’,5,5’-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells. Exp Hematol 34: 1377–1384
  15. 14.Murias M, Handler N, Erker T et al. (2004) Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. Bioorg Med Chem 12: 5571–5578
  16. 15.Benitez DA, Pozo-Guisade E, Alvarez-Barrientos A et al. (2007) Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines. J Androl 28: 282–293
  17. 16.Kampa M, Hatzoglou A, Notas G et al. (2000) Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines. Nutr Cancer 37: 23–33

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