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Emodin

Epimedium extract icariin 

Epimedium extract icariin

Product Name: Epimedium Extract
CAS No.: 489-32-7
Molecular Formula: C33H40O15 
Active ingredients: Icariin, Icariins
Specification: Icariin 5%-98%   
Use Part : Leaf 
Appearance: Brown powder
Mesh size:80 Mesh
Test Method: HPLC

Epimedium extract is prepared from Epimedium grandiflorum,Epimedium extract, also known as horny goat weed extract has been used to treat male erectile dysfunction. Epimedium extract powder icariin can increase the production of sperm, stimulate the sensing nerves, and indirectly promote sexual desire. Epimedium extract is ideal for adding to sexual enhancement formulas.

 

Epimedium extract main function:

(1) Stimulate nervous system, promoting sexual function.
(2) Antibacterial, anti-inflammatory, antitussive, anti-asthmatic and eliminating phlegm.
(3) Tonifying kidney and boosting male virility, alleviating rheumatism, strengthening the muscles and bones.
(4) Lowering blood pressure and blood sugar.
(5) Anti-cancer and enhancing immunity
(6) Restraining staphylococcus and delaying aging.

 

Epimedium extract Application:

1. Applied in food field, it is mainly used as food additives, it also can be added into many kinds of product;
2. Applied in health product field, it has good effect for cardiovascular diseases and cancer;
3. Applied in pharmaceutical field, it can be used to prevent variety of cardiovascular disease.

 

For more product information pls contact email sales09@staherb.cn

 

Basic Information

Product name

Epimedium P.E

Plant Latin name

Epimedium brevicomum Maxim.

Used part

Leaves and stem

Assay

Icariin 40.00%

Organoleptic

Appearance

Fine Powder

Color

Brownish green

Odor

Characteristic

Taste

Characteristic

Drying Method

Vacuum drying

Excipient

None

Physical Characteristics

Particle Size

100%Through 80 mesh

Loss on Drying

5.0%

Ash content

5.0%

Heavy metals

Total Heavy Metals

≤10ppm

Arsenic

≤0.5ppm

Pb

≤1.0ppm

Microbiological Tests

Total Plate Count

≤1000cfu/g

Total Yeast & Mold

≤100cfu/g

E.Coli

Negative

Salmonella

Negative

Staphylococcus

Negative

 

References:

 

  1. 1.

    Davison S, Davis SR (2003) Hormone replacement therapy: current controversies. Clin Endocrin 58:249–261

  2. 2.

    Sakamoto S, Sassa S, Kudo H et al (2000) Preventive effects of a herbal medicine on bone loss in rats treated with a GnRH agonist. Euro J Endocrinol 143:139–142 

  3. 3.

    Yamaguchi M, Hashizume M (1994) Effect of beta-alanyl-L-histidinato zinc on protein components in osteoblastic MC3T3-El cells: increase in osteocalcin, insulin-like growth factor-I and transforming growth factor-beta. Mol Cell Biochem 136:163–169

  4. 4.

    Relea P, Revilla M, Ripoll E et al (1995) Zinc, biochemical markers of nutrition, and type I osteoporosis. Age Aging 24:303–307

  5. 5.

    Saltman PD, Strause LG (1993) The role of trace minerals in osteoporosis. J Am Coll Nutr 12:384–389

  6. 6.

    Seo JH, Jin YH, Jeong HM et al (2009) Calmodulin-dependent kinase II regulates Dlx5 during osteoblast differentiation. Biochem Biophys Res Commun 384:100–104

  7. 7.

    Reid IR, Ames RW, Evans MC et al (1993) Effect of calcium supplementation on bone loss in postmenopausal women. N Engl J Med 328:460–464

  8. 8.

    Keen CL, Zidenberg-Cherr S (1996) Manganese. In: Ziegler EE, Filer LJ (ed) Present knowledge in nutrition, 7th edn. ILSI Press, Washington D.C, pp 334–343 

  9. 9.

    Hidaka S, Okamoto Y, Nakajima K et al (1997) Preventive effects of traditional chinese (Kampo) medicines on experimental osteoporosis induced by ovariectomy in rats. Calcif Tissue Int 61:239–246

  10. 10.

    Xie F, Wu CF, Lai WP et al (2005) The osteoprotective effect of Herba epimedii (HEP) extract in vivo and in vitro. Evid Based Complement Alternat Med 2:353–361

  11. 11.

    Chen KM, Ge BF, Ma HP et al (2004) The serum of rats administered flavonoid extract from Epimedium sagittatum but not the extract itself enhances the development of rat calvarial osteoblast-like cells in vitro. Pharmazie 59:61–64

  12. 12.

    Chen HL, Liu XY (1989) A probe into the relationship between virtue of Chinese medicine and four trace elements. Chin J Chin Mater Med 14:36–39

  13. 13.

    Zhao J, Jin RG, Luo L (2007) A correlation between the anti-HIV properties of Chinese medicinal herbs and their trace element content. J Beijing Univ Chem Technol 34:467–471 

  14. 14.

    Cheng Y, Wang NL, Wang XL et al (2006) Chemical constituents from Epimedium koreanum Nakai. Journal of Shenyang Pharmaceutical University 23:644–647 

  15. 15.

    Li XH, Zhang JC, Sui SF et al (2005) Effect of daidzin, genistin and glycitin on the osteogenic and adipogenic differentiation of bone marrow stromal cells and the adipocytic trans-differentiation of osteoblasts. Acta Pharmacol Sin 26:1081–1086 

  16. 16.

    Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Meth 65:55–63

  17. 17.

    Gray TK, Flynn TC, Gray KM et al (1987) 17 beta-estradiol acts directly on the clonal osteoblastic cell line UMR106. Proc Natl Acad Sci USA 84:6267–6271

  18. 18.

    Siggelkow H, Schulz H, Kaesler S et al (1999) 1, 25 Dihydroxyvitamin-D3 attenuates the confluence-dependent differences in the osteoblast characteristic proteins alkaline phosphatase, procollagen I peptide, and osteocalcin. Calcif Tissue Int 64:414–421

  19. 19.

    Kostyuk VA, Potapovich AI, Vladykovskaya EN et al (2001) Influence of metal ions on flavonoid protection against asbestos-induced cell injury. Arch Biochem Biophys 385:129–137


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