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madecassoside
Asiaticoside
madecassic acid
Centella total glucosides
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Centella total glucosides 

centella total glucosides

Latin Name: Centella Asiatica(L.) Urban
Product Specification:
10%- 80% Total Triterpenoid Glycosides/Triterpenes
Madecassoside 90%-95%
Asiaticoside(s) 5%-95%
Asiatic Acid 95% HPLC
Madecassic Acid 95%
Part of the Plant Used: Herb(Dried, 100% Natural)
CAS NO.: 84696-21-9

About centella asiatica 

Centella asiatica grows in tropical swampy areas.The stems are slender, creeping stolons, green to reddish-green in color, connecting plants to each other. It has long-stalked, green, reniform leaves with rounded apices which have smooth texture with palmately netted veins. The leaves are borne on pericladial petioles, around 2 cm. The rootstock consists of rhizomes, growing vertically down. They are creamish in color and covered with root hairs.

The flowers are pinkish to red in color, born in small, rounded bunches (umbels) near the surface of the soil. Each flower is partly enclosed in two green bracts. The hermaphrodite flowers are minute in size (less than 3 mm), with 5-6 corolla lobes per flower. Each flower bears five stamens and two styles. The fruit are densely reticulate, distinguishing it from species of Hydrocotyle which have smooth, ribbed or warty fruit.The crop matures in three months, and the whole plant, including the roots, is harvested manually.

 

Main function:

1.Gotu Kola Extract has function of hearing heat and detoxicating,

2.Gotu Kola Extract can induce diuresis and reduce edema.

3.Gotu Kola Extract has function of brain refreshing.

4.Gotu Kola Extract has the function of nourishing,  diminish inflammation,  heal wounds or ulcers,  diuresis purge and calming.

5.Gotu Kola Extractcan can also treat leprosy, ulcer.

6.Gotu Kola Extract has wave action to blood purification and immunity.

7.Gotu Kola Extract is a very good Nerve tonic, could improve memory, reduce mental fatigue;

8.Gotu Kola Extract can reduce blood press, treat liver disease.

9.Gotu Kola Extract has function of antibacterial action.

 

Centella asiatic extract Benefits:

 

Anti gastric ulcer effect
The extract of Centella asiatica can improve the level of GABA in the brain of rats with gastric ulcer, and also reduce the secretion of gastric acid and the activity of pepsin, showing a good anti ulcer effect.
2. Enhance memory
3. Effect on central nervous system
Centella asiatica extract has strong central inhibition and cholinergic effect.
4. Antibacterial effect
The water extract of Centella asiatica has antibacterial and antiviral effects, and can inhibit Pseudomonas aeruginosa, Proteus and Staphylococcus aureus
5. Stimulate biosynthesis
The total triterpenoid extract of Centella asiatica can significantly affect cell proliferation, protein and proteoglycan biosynthesis, and increase collagen and fibronectin.
6. Effect on skin tissue
It can accelerate wound healing, promote skin growth, increase local white blood cells, hyperplasia of vascular network of connective tissue, and increase mucus secretion.

 

Widely used in health products, cosmetics, medicine.

 

For more product inforamtion pls contact email sales09@staherb.cn

References:

   1. Polensky J, Sach E, Lederer E (1959) Sur la constitution chimique de la partie glucidique de l’asiaticoside. Bull Soc Chim Fr 880–887

  1. 2.
    Luo SQ, Chin HF (1980) Isolation and identification of asiaticoside from Centella asiatica (L.) Urban. Chin Trad Herb Drugs 11:244–246
  2. 3.
    Polonsky J (1953) Sur la constitution chimique de l’acide asiatique, aglycone de l’asiaticoside. Rattachement de l’acide asiatique à la série de l’α-amyrine; formule développée de l’acide asiatique. Bull Soc Chim Fr 173–180
  3. 4.
    Pinhas H (1969) Structure de l’acide madasiatique, nouvel acide triterpénique isolé de Centelle asiatica L. Bull Soc Chim Fr 3592–3595
  4. 5.
    Pinhas H, Billet D, Heitz S, Chaigneau M (1967) Structure de l’acide madécassique, nouveau triterpène de Centella asiatica de Madagascar. Bull Soc Chim Fr 1890–1895
  5. 6.
    Singh B, Rastogi RP (1968) Chemical examination of Centella asiatica. III. Constitution of brahmic acid. Phytochemistry 8:1385–1393
  6. 7.
    Lou SQ, Jin HF (1981) Isolation and identification of madecassoside in Centella asiatica. Chin Trad Herb Drugs 12:5–6
  7. 8.
    Asakawa Y, Matsuda R, Takemoto T (1982) Mono- und sesquiterpenoids from Hydrocotyle and Centella species. Phytochemistry 21:2590–2592
  8. 9.
    Schulte KE, Ruecker G, Abdul Bary E (1973) Constituents of medical plants. XXVII. Poly-acetylenes from Hydrocotyle asiatica. Arch Pharm (Weinheim) 306:197–209
  9. 10.
    Bohlmann F, Zdero C (1975) Polyacetylenic compounds. CXXX. A new polyene from Centella species. Chem Ber 108:511–514
  10. 11.
    Prum N, Illel B, Raynaud J (1983) Flavonoid glycosides from Centella asiatica L. (Umbellife-rae). Pharmazie 38:423
  11. 12.
    Ramaswamy AS, Periyasamy SM, Basu NK (1970) Pharmacological studies on Centella asiatica. J Res Indian Med 4:160–175
  12. 13.
    Tsurumi K, Hiramatsu Y, Hayashi M, Fujimura H (1973) Effect of madecassol on wound healing. Oyo Yakuri 7:833–843 (CA 80:66674f)
  13. 14.
    Poizot A, Dumez D (1978) Modification of the healing kinetics after iterative exeresis in the rat. Action of titrated extract of Centella asiatica (TECA) on duration of healing. C R Acad Sci [D] 286:789–792
  14. 15.
    Boiteau P, Ratsimamanga AR (1956) Asiaticosid, extracted from Centella asiatica, its therapeutic uses in the healing of experimental or refractory wounds, leprosy, skin tuberculosis and lupus. Therapie 11:125–149
  15. 16.
    Viala A, Cano JP, Durand A, Paulin R, Roux F, Placidi M, Pinhas H, Lefournier C (1977) Animal study of the transcutaneous passage of tritium-labeled active principles from Centella asiatica L. applied in a continuous oil phase or an oil-water emulsion. Therapie 32:573–583
  16. 17.
    Del Vecchio A, Senni I, Cossu G, Molinaro M (1984) Effects of Centella asiatica on biosynthetic activity in cultured fibroblasts. Farmaco [Prat] 39:355–364

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