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Astragalus extract 

Astragalus extract cycloastragenol 

Product Name: Astragalus Root Extract

Latin Name: Astragalus membranaceus

Active ingredient:Astragaloside A,cycloastragenol,Polysaccharides 

Part of the Plant Used: Root

Test method:HPLC/UV

 

 

About Astragalus

 

Astragalus root has been used and applied as a general tonic and herbal adaptogen,treat uterine bleeding and boost immune system,suggest to treat cancer,tumor and other immune related problems such as AIDS,release antiviral effects and useful for treatment of liver diesease(liver Fibrosis and Liver cirrhosis) and act as antibiotics,help liver detoxification,and good for treatment of Myocarditis(heart infections), suggest for treatment of kidney related problems such as renal failure,diabetic nephropathy(DN), acute renal injury,Type 1 diabetic and Type 2 diabetic,and other chronic kidney diseases.Astragalus root got find works nice for man of infertility,Chronic Fatigue Syndromewhich may bad to immune system,to treat heart disease including coronary artery related disease,heart failure and Cardiovascular Disease,and insufficient placental blood supply,support for blood deficiency and hematopenia,protect lung and prevent upper respiratory tract infection,help to smoking cessation,benefit for digestive tract and Colitis treatment,induce growth hormone.

 

Cycloastragenol has a similar chemical structure to that of the Astragaloside IV molecule, but it is smaller and significantly more bioavailable, enabling lower doses to be taken. It is already used as an immunostimulant because of its ability to increase T lymphocyte proliferation. However, it is its exceptional anti-aging properties that are of increasing interest to the scientific community. Cycloastragenol stimulates the repair of DNA damage by activating telomerase, a nucleoprotein enzyme which catalyses synthesis and growth of telomeric DNA. Telomeres are made of thin filaments and are found at the tips of chromosomes. Maintaining their stability enables cells to avoid replicative senescence and indefinite proliferation beyond the ‘Hayflick limit'. Telomeres shorten with each cycle of cell division, or when subjected to oxidative stress. Until now, this has been an unavoidable mechanism of aging.

 

What is the functions of Astragalus root extract?  

1.Studies have documented that Astragalus boosts activity of several kinds of white blood cells and increases production of antibodies and interferon, the body own natural anti-viral agent.                                                   

2.Improve immunity.
3.It is a first class herb for maintaining a healthy immune system.
4.As an immune system tonic, Astragalus It helps the body to fight off external pathogens that you may come  in contact with.                                     

5.It thus directly supports the Lung and Spleen organs in the body. By supporting those organs, energy derived from the foods and the air is increased.
6.Cardial activity on exhausted heart, Hypotensive activity, Diuretic activity, Sedative effect, Immunity enhancer.                                            

 How about the applications of Astragalus root extract? 

1. Pharmaceutical stuff.

2. Functional food and food additive.

3. Livestock products and poultry products.

4. Water-soluble beverages.  

5. In heart cerebrovascular aspect,it can inhibit platelet aggregation, reduce blood viscosity and coagulation, relax smooth muscle, expand of cerebrovascular, reduce vascular resistance, improve blood circulation, especially improve the microcirculation, can also inhibit the formation of arterialthrombosis.

 

For more product information pls contact email sales09@staherb.cn

References:

 

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    M. Ya. Sokolov and M. V. Zamotaev, Handbook on Medicinal Herbs (phytotherapy), Meditsina, Moscow (1988).

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    P. A. Galenko-Yaroshevskii (ed.), Pharmacological Regulation of Vascular Tone, Russian Academy of Medical Sciences Press, Moscow (1999).

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    Y. H. Cai, Z. Qin, and Q. L. Yao, “A prospective, pilot study of Astragalus membranaceus in the treatment of acute cerebral infarction,” J. Clin. Neurol., No. 7, 216–218 (1994).

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    I. Heuser and C.-H. Lammers, “Stress and the brain,” Neurobiol. Aging24, S69–S76 (2003).

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    A. Jalsrai, G. Grecksch, and A. Becker, “Evaluation of the effects of Astragalus mongholicus Bunge saponin extract on central nervous system functions,” J. Ethnopharmacol.131, 544–549 (2010).

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    Y. J. Lee, B. Choi, E. H. Lee, et al., “Immobilization stress induces cell death through production of reactive oxygen species in the mouse cerebral cortex,” Neurosci. Lett.392, 27–31 (2006).

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    Y. Luo, Z. Qin, Z. Hong, “Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia,” Neurosci. Lett.363, 218–223 (2004).

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    S. Makino, K. Hashimoto, and P. W. Gold, “Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress,” Pharmacol. Biochem. Behav.73, 147–158 (2002).

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    S. Toda and Y. Shirataki, “Inhibitory effects of Astragali radix, a crude drug in Oriental medicines, on lipid peroxidation and protein oxidative modification of mouse brain homogenate by copper,” J. Ethnopharmacol.68, 331–333 (1999).

  16. 16.

    D. Yu, Y. Duan, Y. Bao, et al., “Isofl avonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate,” J. Ethnopharmacol.98, 89–94 (2005).

  17. 17.

    B. Q. Zhang, S.-J. Hu, L.-H. Qiu, and J.-H. Zhu, “Effects of Astragalus membranaceus and its main components on the acute phase endothelial dysfunction induced by homocysteine,” Vascul. Pharma col.46, 278–285 (2007).


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