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chamomile flower extract Apigenin

Item name:Chamomile flower extract
Specification: 1%- 98% Apigenin 5:1-20:1
Botanical Name: Matricaria chamomilla L.
Appearence: Brown fine powder
Active Ingredients: Apigenin                       
CAS NO.: 520-36-5                  
Molecular formula: C15H10O5

About chamomile extract 

Chamomile is the common name for several daisy-like plants of the family asteraceae, that are commonly used to make herb infusion that can help to induce sleep. Because chamomile can cause uterine contractions that can cause miscarriage, it should not be taken during pregnancy or breast-feeding.

Apigenin is a natural antioxidant, which can inhibit the activity of carcinogenic substances; as an antiviral drug to treatment for HIV and other virus-infected; treat various inflammations; calm and soothe the nerves; buck. Compared With other flavonoids (quercetin, kaempferol flavonoids), Apigenin is low toxicity and no mutagenicity.


Apigenin main function:

1. Chamomoile extract apigenin has long been used as an after-meal and bedtime drink;

2. Chamomile extract apigenin used for it's soothing effects and ability to support normal tone in the digestive tract;

3. Chamomoile extract apigenin used for a variety of ailments including: colic (especially in children), bloat,mild upper respiratory infections,premenstrual pain, anxiety and insomnia;

4. Chamomilr extract apigenin treat sore and chapped nipples in nursing mothers, as well as minor skin infections and abrasions. Eye drops made from these herbs are also used for tired eyes and mild ocular infections.


Apigenin Application:

1.It is used in the food industry as a spice for meat dishes, and is used in soups and sauces.
2.In natural medicine, it is used as diureticum against bladder and kidney trouble and for therapy against inflammation.

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Safety Concerns

Apigenin seems to be very safe chemical, without any dangerous side effects, flavonoid can interact with chemotherapy drugs.It is, by itself, a potent chemotherapeutic agent.

5. Dosage Information

For general health and well-being, doses found in multiple servings of fruits and vegetables is adequate.For anxiolytic effects, doses in the range of 3-10 mg/kg bodyweight are effective without sedation, and higher doses induce sedation in addition to reductions in anxiety.



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47.Bisabololoxide A, one of the main constituents in German chamomile extract, induces apoptosis in rat thymocytes
German chamomile (Matricaria recutita L.), one of the popular ingredients in herbal teas, has been traditionally used for medicinal purposes. Bisabololoxide A (BSBO) is one of the main constituents in this herb. ...

Ikuko Ogata, Takuya Kawanai, Erika Hashimoto, Yumiko Nishimura… in Archives of Toxicology (2009)

48.Usefulness of Transgenic Luminescent Bacteria in Direct Bioautographic Investigation of Chamomile Extracts
Direct bioautography performed with luminescence gene-tagged bacteria enables almost real-time detection of antimicrobial compounds in plant extracts. This method for the detection of chamomile (Matricaria recuti...

Ágnes M. Móricz, Ernő Tyihák, Péter G. Ott in JPC – Journal of Planar Chromatography – M… (2010)

49.Chamomile extract/coffea/commiphora molmol
Reactions Weekly (2017)

50.Preliminary examination of the efficacy and safety of a standardized chamomile extract for chronic primary insomnia: A randomized placebo-controlled pilot study
Despite being the most commonly used herbal for sleep disorders, chamomile's (Matricaria recutita) efficacy and safety for treating chronic primary insomnia is unknown. We examined the preliminary efficacy and sa...

Suzanna M Zick, Benjamin D Wright, Ananda Sen… in BMC Complementary and Alternative Medicine (2011)

51.Biological activities of chamomile (Matricaria chamomile) flowers’ extract against the survival and egg laying of the cattle fever tick (Acari Ixodidae)
In the present work, the potential of acaricidal activity of chamomile flowers’ extract was studied against engorged Rhipicephalus annulatus tick under laboratory condition. For this purpose, the engorged females...

Khodadad Pirali-Kheirabadi… in Journal of Zhejiang University SCIENCE B (2007)

52.P02.118. Oral chamomile (Matricaria recutita) extract therapy of Generalized Anxiety Disorder (GAD): trial in progress
J Mao, R Derubeis, Q Li, J Baier… in BMC Complementary and Alternative Medicine (2012)

53.Chamomile Methanolic Extract Mitigates Small Bowel Inflammation and ROS Overload Related to the Intestinal Nematodes Infection in Mice
Chamomile (Matricaria recutita...L.) is a plant which has been reported to be effective in treating several parasitic and digestive diseases. The present study was conducted to evaluate the anthelmintic activity ...

Soumaya Hajaji, Mohamed-Amine Jabri, Dhouha Alimi, Mourad Rekik… in Acta Parasitologica (2019)

54.Chamomile decoction extract inhibits human neutrophils ROS production and attenuates alcohol-induced haematological parameters changes and erythrocytes oxidative stress in rat
The aim of this study was to evaluate the protective effects of subacute pre-treatment with chamomile (Matricaria recutita L.) decoction extract (CDE) against stimulated neutrophils ROS production...

Mohamed-Amine Jabri, Mamane Sani, Kais Rtibi… in Lipids in Health and Disease (2016)

55.Quantitative proteomics analysis of the treatment of asthma rats with total flavonoid extract from chamomile
Asthma is a chronic immune disease that has become a serious public health problem. The currently available medications are not ideal because of their limitations and side effects; hence, new target proteins and ...

Qian Li, Shengjun Zhao, Jun Lu, Xiaolong Kang, Gang Zhang… in Biotechnology Letters (2020)

56.In-Situ Clean-Up and OPLC Fractionation of Chamomile Flower Extract to Search Active Components by Bioautography
Bioassay-guided isolation of antibacterial components of chamomile flower methanol extract was performed by overpressured layer chromatography ( in the adsorbent bed after off-line sample applicatio...

Emil Mincsovics, Péter G. Ott, Ágnes Alberti… in JPC – Journal of Planar Chromatography – M… (2013)

57.The response of serum Glypican-4 levels and its potential regulatory mechanism to endurance training and chamomile flowers’ hydroethanolic extract in streptozotocin–nicotinamide-induced diabetic rats
Glypican-4 (GPC-4) is a novel adipomyokine that enhances insulin signaling. Glycosylphosphatidylinositol-specific phospholipase D (GPLD1) is thought to release GPC-4 and is itself an insulin-regulated enzyme. Ben...

Farzad Abdolmaleki, Ali Heidarianpour in Acta Diabetologica (2018)

58.Evaluation of the Extraction Efficiency of Biologically Active Compounds from Chamomile Flowers (Chamomilla recutita R.) Grown in the Samara Region by Extractants in the Subcritical State
Extracts of biologically active compounds (BACs) from chamomile flowers grown in the Samara region produced ... gravimetry. Identification of BACs in the produced extracts was carried out using reactive gas chrom...

L. V. Pavlova, I. A. Platonov, V. A. Kurkin… in Russian Journal of Physical Chemistry B (2018)


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