Sialic acid Sialic acid is a derivative of a 9-carbon monosaccharide. The name comes from the Greek word (σιαλοσ (sialos) ‘saliva’) which is a negatively charged ion that gives saliva a smooth feel. Not only does it have the effect of "inducing" invading bacteria, cognition is a transmitter of gangliosides, and it is an integral part of the brain.
Sialic acid (SA), scientifically called "N-acetylneuraminic acid", is a naturally occurring carbohydrate. It was originally isolated from the submandibular gland mucin, hence the name. Sialic acid is usually present in the form of oligosaccharides, glycolipids or glycoproteins. In the human body, the brain has the highest sialic acid content. The content of sialic acid in the gray matter of the brain is 15 times that of internal organs such as liver and lung. The main food source of sialic acid is breast milk, which is also found in milk, eggs and cheese.
Chinese name: N-acetylneuraminic acid
English name: N-Acetylneuraminic acid
Alias name: sialic acid aceneuraric acid N-acetylmannosamine pyruvate N-acetylsialic acid
Other aliases: 5-Acetamido-3,5-dideoxy-D-glycero-D-galactonulosonic acid o-Sialic acid Galactononulosonic acid Lactaminic acid NANA N-Acetylsialic acid
Molecular formula: C11H19NO9
Molecular weight: 309.27
CAS Number: 131-48-6
MDL number: MFCD00006620
EINECS No.: 205-023-1
BRN number: 1716283
PubChem No.: 24890457
Properties: Colorless crystal.
Melting point (ºC): 185-187 (decomposition)
Specific rotation (º, C=2, in water): -32
Solubility: soluble in water and methanol, slightly soluble in ethanol, insoluble in ether, acetone and chloroform. 
Clinical significance: Sialic acid is N-acetylneuraminic acid or any of its esters or derivatives of its alcohol hydroxyl group, located at the end of the side chain of cell membrane glycoproteins, and is an important part of receptors on the cell membrane surface. The increase in malignant tumors, such as lung cancer, gastric cancer, colon cancer, liver cancer, ovarian cancer.
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