白藜芦醇
品名:白藜芦醇
来源:虎杖
CAS号:501-36-0
分子式:C14H12O3
检测方式: HPLC
虎杖是蓼科的植物之一,其原生长于东亚并广泛分布于中国。虎杖在中国和日本传统医药中被用于治疗多种病痛,其中包括霉菌感染,多种皮肤炎症,心血管疾病和肝脏疾病等。 白藜芦醇和大黄素是虎杖中的主要功能成分。研究显示白藜芦醇和大黄素表现出广泛的抗氧化特性,如LDL胆固醇氧化和脂质过氧化反应。白藜芦醇同时显示出有助于心血管健康和活血,减轻疼痛,清热去湿,去毒去痰。其它成分包括丹蒽酮,大黄素甲醚和大黄酸都具有抗炎症,祛关节炎和抗微生物活性。
上禾生物专业生产虎杖提取物白藜芦醇,大黄素等。价格优惠,随时发货。产品详询:13657416805
- 参考文献:
- 1.Baur JA, Sinclair DA (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5: 493–506
- 2.Bemis DL, Katz AE, Buttyan R (2006) Clinical trials of natural products as chemopreventive agents for prostate cancer. Expert Opin Investig Drugs 15: 1191–200
- 3.Aggarwal BB, Bhardwaj A, Aggarwal RS et al. (2004) Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res 24: 2783–2840
- 4.Joe AK, Liu H, Suzui M et al. (2002) Resveratrol induces growth inhibition, S phase arrest, apoptosis and changes biomarker expression in several human cancer cell lines. Clin Cancer Res 8: 893–903
- 5.Soleas GJ, Grass L, Josephy PD et al. (2006) A comparison of the anticarcinogenic properties of four red wine polyphenols. Clin Biochem 39: 492–497
- 6.Providencia R (2006) Cardiovascular protection from alcoholic drinks: scientific basis of the French Paradox. Rev Port Cardiol 25: 1043–1058
- 7.Ovesna Z, Kozics K, Bader Y et al. (2006) Antioxidant activity of resveratrol, piceatannol and 3,3’,4,4’,5,5’-hexahydroxy-trans-stilbene in three leukemia cell lines. Oncol Rep 16: 617–624
- 8.Athar M, Back JH, Tang X et al. (2007) Resveratrol: A review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol (in press)
- 9.Ovesna Z, Horvathova-Kozics K (2005) Structure-activity relationship of trans-resveratrol and its analogues. Neoplasma 52: 450–455
- 10.Pezutto JM (2004) Resveratrol: a whiff that induces a biologically specific tsunami. Cancer Biol Ther 3: 889–890
- 11.Aziz MH, Nihal M, Fu VX et al. (2006) Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3’-kinase/Akt pathway and Bcl-family proteins. Mol Cancer Ther 5: 1335–1341
- 12.Liao Z, Mason KA, Milas L (2007) Cyclo-oxygenase-2 and its inhibition in cancer: is there a role? Drugs 67: 821–845
- 13.Horvath Z, Murias M, Saiko P et al. (2006) Cytotoxic and biochemical effects of 3,3’,4,4’,5,5’-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells. Exp Hematol 34: 1377–1384
- 14.Murias M, Handler N, Erker T et al. (2004) Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. Bioorg Med Chem 12: 5571–5578
- 15.Benitez DA, Pozo-Guisade E, Alvarez-Barrientos A et al. (2007) Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines. J Androl 28: 282–293
- 16.Kampa M, Hatzoglou A, Notas G et al. (2000) Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines. Nutr Cancer 37: 23–33
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