Paclitaxel, a natural anticancer drug with a molecular formula of C47H51NO14, has been widely used in the treatment of breast cancer, ovarian cancer and some head and neck cancers and lung cancers. As a diterpene alkaloid compound with anticancer activity, paclitaxel has been favored by botanists and chemists due to its novel and complex chemical structure, extensive and significant biological activities, new and unique mechanism of action, and lack of natural resources. , pharmacologists, and molecular biologists have greatly favored it, making it a world-renowned anti-cancer star and research focus in the second half of the 20th century.
After 8 years, Li Chuangchuang's research group of SUSTech has completed the efficient total synthesis of the famous anti-cancer natural drug paclitaxel.
Foreign name: taxol
Chemical formula: C47H51NO14
Molecular weight: 853.91
CAS Registration Number: 33069-62-4
EINECS accession number: 205-285-7
Melting point: 213 ℃
Boiling point: 957.1 ℃
Water solubility: insoluble in water
Density: 1.39 g/cm³
Appearance: white crystalline powder
Flash point: 532.6 ℃
Safety Description: S22; S26; S36/37/39; S45
Hazard symbols: R40; R41
Hazard Description: Xn
Category: Prescription Drugs
Main indications: Physiological function of ovarian cancer, breast cancer and anti-cancer
Address: Room 202, Building B8, Huanchuang Enterprise Square, Lugu Street, Yuelu District, Changsha City, Hunan Province
Business scope: Biotechnology, research and development of plant extracts (can be used in the field of pharmaceutical and health products, cosmetics, feed additives and biological pesticide production and development)
Main products: Eucommia extract - chlorogenic acid (5%-98%), ursolic acid (25%-98%), corosolic acid (1%-98%), bitter amygdalin (50%-98%), epimedoside (10%-98%) and other standardized high-purity plant extracts.
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