This product is the extract of Astragalus mongolica or Astragalus membranaceus, containing Astragalus polysaccharide in glucose (C6H12O6), oral liquid grade should be not less than 65%, injection grade should be not less than 70%.
Properties： This product is brownish yellow powder, slightly sweet taste, with moisture inducing properties.
Function and Use：It has the effect of anti-immunosuppressant, regulating blood sugar in the body, enhancing the effect of humoral immunity, and also has the effect of anti-tumor.
1、Immunomodulatory activity of astragalus polysaccharide
Astragalus polysaccharide can significantly enhance non-specific immune function and humoral immune function, significantly enhance the phagocytosis of mouse macrophages, promote the formation of serum hemolysin, improve the hemolytic function of vacuole-forming cells and significantly increase the weight of spleen.
Astragalus polysaccharide has obvious inhibitory effect on a variety of experimental tumor oil. Animal experiments show that Astragalus polysaccharide and IL-2/LAK anti-tumor effect is similar, and has a significant enhancement of IL-2/LAK anti-tumor effect. The application of the two together can significantly improve the killing power of LAK cells on target cells. The dynamic cellular immune function observation of the combination of the two suggested that both of them had the effect of resisting the decrease of NK cell activity and IL-2 production capacity in murine spleen. It indicates that the anti-tumor effect of Astragalus polysaccharide is related to the effect of enhancing the immune function of the body. It can improve the immune function caused by tumor of the body, promote the activation of immune cells to release endogenous factors, prevent peroxidation thus causing the killing and inhibiting effect on tumor cells, and be used for the treatment of chicken Malik's disease.
3、The effect on trauma infection
Pharmacological experiments of Astragalus polysaccharide on experimental mouse trauma showed that it can significantly enhance the intensity of phagocytosis luminescence of macrophages and inhibit the release of PCE2, further promoting the release of TNF. The combination of immune activator astragalus polysaccharide and cyclooxygenase inhibitor ibuprofen both enhanced the phagocytic luminescence intensity of macrophages and significantly inhibited the secretion of PGE2, IL-1 of TNF. Thus, the combination of immune activator and cyclooxygenase inhibitor can be expected to be a new protocol for drug treatment of trauma infection.
Zhang Yan et al. found that Astragalus polysaccharide has obvious protective effect on experimental liver injury, and can significantly counteract the serum glutamate transaminase induced by carbon tetrachloride and paracetamol in mice, and has obvious protective effect on the pathological tissue changes induced by both of them.
5、Regulatory effect on blood sugar
APs have a bidirectional regulatory effect. It can be a significant reduction of blood glucose in glucose-loaded mice, and can also significantly counteract the response of elevated blood glucose in mice caused by adrenaline, and it can also significantly counteract experimental hypoglycemia in mice caused by phenylephrine. But it has no obvious effect on insulin hypoglycemia.
6、Astragalus polysaccharide antiviral effect
Is an interferon inducer, its antiviral principle: stimulate the function of macrophages and T cells, so that the number of E ring-forming cells increase, induce cytokines, promote interleukin induction, and the animal body to produce endogenous interferon, so as to achieve the purpose of antiviral, for the treatment of piglet circovirus disease, chicken infectious bursal disease, influenza Ai viral infectious diseases. Astragalus can prevent colds and reduce the incidence of more than 50%, astragalus and interferon combined application can reduce the incidence of more than 70%.
7、Astragalus polysaccharide anti-bacterial effect.
The mechanism of antibacterial action is multifaceted, on the one hand, the drug is the direct inhibition and detoxification of fine dispersion and its toxic products, on the other hand, the main thing is to mobilize the body's immune defense function and wield the support of the evil and antibacterial, bactericidal effect. Shigella dysentery bacillus, Bacillus anthracis, a, b type lysis streptococcus pneumoniae, Streptococcus aureus, Escherichia coli, Salmonella have antibacterial have antibacterial effect.
8、Astragalus polysaccharide in the application of livestock health care.
(1) Astragalus as a feed additive in animal breeding
In recent years, due to the increased awareness of the toxic side effects of chemical synthetic drugs, the domestic and foreign pharmaceutical industry began to pay attention to the development of natural plant pharmaceuticals. The need to develop herbal additives with less toxic side effects, significant efficacy and both medicinal and nutritional properties is becoming more and more urgent, and Astragalus has started to be used in livestock production as a herbal feed additive to support the capital and strengthen the integrity of the class.
Astragalus polysaccharide has the function of improving the utilization of nutrients and promoting animal growth. Astragalus polysaccharide contains amino acids, vitamins, trace elements and other nutrients; it contains unknown growth factor (UGF). As feed additives can significantly improve the growth rate of livestock and poultry, enhance the body resistance, improve the quality and yield of meat, eggs and milk.
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Business scope: Biotechnology, research and development of plant extracts (can be used in the field of pharmaceutical and health products, cosmetics, feed additives and biological pesticide production and development)
Main products: Eucommia extract - chlorogenic acid (5%-98%), ursolic acid (25%-98%), corosolic acid (1%-98%), bitter amygdalin (50%-98%), epimedoside (10%-98%) and other standardized high-purity plant extracts.
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