Pharmacological effects 1. Anti-cardiovascular disease populins have made great progress in the research of anti-atherosclerosis, ischemia-reperfusion injury, myocardial infarction and hypertensive disease. In vitro experiments have found that flavonol compounds such as prunetin can dose-dependently inhibit the glycation of LDL, while reducing the electrophoretic migration of glycated LDL, so it can reduce the risk of atherosclerosis in diabetic patients. The continuous administration of yangmeiin 100 and 300 mg/kg for 21 d to myocardial infarction model mice both increased the scavenging of superoxide radicals and reversed the myocardial cell membrane damage and lymphocyte infiltration induced by isoproterenol in rats with myocardial infarction. 2.Antitumor populins can play an antitumor role by inhibiting the growth and proliferation of tumor cells, inhibiting tumor cell metastasis and promoting tumor cell apoptosis. It has been shown that yangmeiin 10μmol/L can significantly inhibit the malignant transformation and proliferation of epidermal Chemicalbook cells in JP6P+ mice by blocking the MEK/ERK/AP-1 signaling pathway; yangmeiin can also inhibit methionine and Akt activity, affect actin cytoskeleton reorganization in myeloblastoma, and curb myeloblastoma cells during metastasis by hepatocyte The antibacterial effect of yangmeiin is closely related to its structure, especially the polyphenol hydroxyl group in its structure; yangmeiin has different degrees of antibacterial effect on Bacillus, Staphylococcus, Streptococcus and Bacillus subtilis. The mechanism of action is through the phenolic hydroxyl group in the structure and the non-specific reaction of the protein in bacteria, resulting in protein inactivation and loss of function.4. Antioxidant effect of prunetin is an excellent antioxidant for oil, the effect is significantly stronger than the synthetic antioxidant BHT (3,5-di-tert-butyl-4-hydroxymethylbenzene) can be used as a natural antioxidant for the preservation of high oil food.5. The damage of the liver.
Address: Room 202, Building B8, Huanchuang Enterprise Square, Lugu Street, Yuelu District, Changsha City, Hunan Province
Business scope: Biotechnology, research and development of plant extracts (can be used in the field of pharmaceutical and health products, cosmetics, feed additives and biological pesticide production and development)
Main products: Eucommia extract - chlorogenic acid (5%-98%), ursolic acid (25%-98%), corosolic acid (1%-98%), bitter amygdalin (50%-98%), epimedoside (10%-98%) and other standardized high-purity plant extracts.
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