Aloe-emodin-an antibacterial active ingredient of rhubarb
Aloe-emodin is an anthraquinone compound with the chemical formula C15H10O5, mainly from the dried roots and rhizomes of Rheum palmatumL, Rheum tanguticum Maxim.ex Balf, or Rheum officinale Baill, family Polygonaceae. The dried roots and rhizomes of .
Aloe rhododendron is an antibacterial active ingredient of rhubarb and is sensitive to bacteria such as Staphylococcus, Streptococcus and bacilli such as diphtheria, chytrid, anthrax, paratyphoid and dysentery, with Staphylococcus and Streptococcus being most sensitive. Aloe rhododendron also has the function of inhibiting the biosynthesis of DNA, RNA and protein of cancer cells
[Chemical Name】1.8-Dihydroxy-3-[hydroxymethyl]-anthraquinone 1,8-Dihydroxy-3-hydroxymethylanthraquinone; 1,8-Dihydroxy-3-( hydroxymethyl)-9,10-anthracenedione; 3-(Hydroxymethyl)chrysazin.
Synonyms】Rhabarberone, Rottlerin, Aloe laxative
Source】Rhizome of Rheum palmatum L., Polygonaceae, Rhizome of R. officinale Baill, Rhizome of Rumex patientia L., Rhizome of R. dentatus L., Root of Cassia mimosoides L., Cassia dentatus L. The seeds of C. tora L., the seeds of C. occidentalis L., the fruits of ^b Rhamnus davurica Pall. of the family Rhamnaceae, the Curassow Aloe and Aloe goodwiniana of the family Liliaceae.
Physical properties]: Orange needle-like crystals (toluene), or earthy yellow crystalline powder. Melting point 223～224°, easy to sublimate. Soluble in acetaldehyde, benzene, hot ethanol, dilute ammonia, sodium carbonate and sodium hydroxide aqueous solution. Easily soluble in hot ethanol. It is yellow in ether and benzene, scarlet in ammonia and sulfuric acid.
Method】Aloe-emodin can be obtained from the crude product of low temperature dried aloe vera juice extracted with ethyl acetate, and then refined by silica gel column chromatography (petroleum ether-ethyl acetate).
Specification】>90%; >98%, thin layer identification only a spot, for a single component.
Storage】 Keep in a cool and dry place.
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