Diosmin

Item name: diosmin 

CAS NO: 520-27-4

Purity:90%

Appearance:light yellow powder

Test method:HPLC

Molecular Formula C28H32O15

Molecular Weight 608.54

 

About Diosmin

Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

 

Diosmin differs molecularly from hesperidin by the presence of a double bond between two carbon atoms in diosmin's central carbon ring. Diosmin can be manufactured by extracting hesperidin from citrus rinds, followed by conversion of hesperidin to diosmin. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.

 

Citrus aurantium extract

Active

Ingredients

Specs

Test Method

Appearance

Solubility

Synephrine

6%-30%

HPLC

Brown-yellow powder

Slightly soluble

in water and

methanol

Hesperidin

10%-98%

HPLC

Yellow to light brown powder

Slightly soluble

in methanol

Hesperetin

10%-98%

HPLC

Yellow to dark brown powder

Slightly soluble

in water and

methanol

Neohesperidin

10%-98%

HPLC

Off-White or light

yellow powder

soluble in hot

water and

ethanol

Diosmin/

Hesperidin

9:1

HPLC

Grayish Yellow or 

yellow powder

Slightly soluble

in water

Citrus Bioflavonoids

10%-90%

HPLC

Brown-yellow powder

Slightly soluble

in water

Nobiletin

98%

HPLC

White Crystalline 

powder

soluble in hot

water and

ethanol

PMFs

(Polymethoxy

Flavones)

10%-98%

HPLC

Yellow to Brown

Partially soluble in hot water and ethanol

NHDC

98%

HPLC

White

soluble in water

Citrus

Polyphenols

10%-90%

HPLC

Yellow to Brown 

soluble in water

 

Function of Diosmin 


1.Diosmin has antioxidant, antiinflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions


2.Diosmin can inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase. 


3.Diosmin can improve the health of capillaries by reducing the capillary permeabilit 


4.Diosmin can be used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. 


5.Diosmin can excite the heart and shrink the blood vessel, and then causes the hypertension.

 

 

Application of Diosmin


1. Applied in food field, it is used as a flavor enhancer and sweetener in a wide variety of alcoholicbeverage, dessert foods and savory foods.


2. Applied in cosmetics, it can added into toothpaste and mouth wash.


3. Applied in pharmaceutical field, it is mainly used to reducing the bitterness of in form.

 

For more product information pls kindly contact email sales09@staherb.cn

 

References:

 

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